Kirilow is a doctor apprentice whose lover Peristrophe is a “starfish,” a woman who can regenerate her own limbs and organs, which she uses to help her clone sisters whose organs are failing. When a denizen from Salt Water City suffering from a mysterious flu comes into their midst, Peristrophe becomes infected and dies, prompting Kirilow to travel to Salt Water City, where the flu is now a pandemic, to find a new starfish who will help save her sisters. There, Kirilow meets Kora, a girl-woman desperate to save her family from the epidemic. Kora has everything Kirilow is looking for, except the will to abandon her own family. But before Kirilow can convince her, both are kidnapped by a group of powerful men to serve as test subjects for a new technology that can cure the mind of the body.